COPB1 antibody (Middle Region)

Catalog No. ABIN630777

Product Details anti-COPB1 Antibody

Target: COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPB1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: COPB1 antibody was raised against the middle region of COPB1

Purification: Affinity purified

Immunogen: COPB1 antibody was raised using the middle region of COPB1 corresponding to a region with amino acids QLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCS

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

COPB1 Blocking Peptide, catalog no. 33R-7619, is also available for use as a blocking control in assays to test for specificity of this COPB1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of COPB1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for COPB1

Target: COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))

Alternative Name: COPB1 (COPB1 Products)

Synonyms: id:ibd5034 antibody, wu:fc66c05 antibody, zgc:92482 antibody, COPB1 antibody, DKFZp459K154 antibody, COPB antibody, 2610019B04Rik antibody, Rack2 antibody, Beta-COP antibody, coatomer protein complex, subunit beta 1 antibody, coatomer protein complex subunit beta 1 L homeolog antibody, coatomer protein complex subunit beta 1 antibody, copb1 antibody, copb1.L antibody, COPB1 antibody, Copb1 antibody

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Molecular Weight: 107 kDa (MW of target protein)