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TNKS1BP1 antibody (Middle Region)

TNKS1BP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630864
  • Target See all TNKS1BP1 Antibodies
    TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
    Binding Specificity
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 30
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 1
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNKS1BP1 antibody is un-conjugated
    Application
    • 18
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Specificity
    TNKS1 BP1 antibody was raised against the middle region of TNKS1 P1
    Purification
    Affinity purified
    Immunogen
    TNKS1 BP1 antibody was raised using the middle region of TNKS1 P1 corresponding to a region with amino acids DGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFIE
    Top Product
    Discover our top product TNKS1BP1 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    TNKS1BP1 Blocking Peptide, catalog no. 33R-1945, is also available for use as a blocking control in assays to test for specificity of this TNKS1BP1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNKS0 P1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
    Alternative Name
    TNKS1BP1 (TNKS1BP1 Products)
    Synonyms
    TAB182 antibody, Tab182 antibody, mKIAA1741 antibody, tankyrase 1 binding protein 1 antibody, 182 kDa tankyrase-1-binding protein antibody, TNKS1BP1 antibody, LOC100625088 antibody, Tnks1bp1 antibody
    Background
    TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
    Molecular Weight
    190 kDa (MW of target protein)
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