UBE2M antibody

Catalog No. ABIN631350

Product Details anti-UBE2M Antibody

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2M antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purified

Immunogen: UBE2 M antibody was raised using a synthetic peptide corresponding to a region with amino acids IKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISF

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

UBE2M Blocking Peptide, catalog no. 33R-4026, is also available for use as a blocking control in assays to test for specificity of this UBE2M antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of UBE0 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for UBE2M

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Alternative Name: UBE2M (ube2m Products)

Synonyms: DDBDRAFT_0204633 antibody, DDBDRAFT_0238042 antibody, DDB_0204633 antibody, DDB_0238042 antibody, UBC-RS2 antibody, UBC12 antibody, hUbc12 antibody, 2510040H03Rik antibody, Ubc-rs2 antibody, ubiquitin conjugating enzyme E2M antibody, ubiquitin-conjugating enzyme E2M antibody, ubiquitin conjugating enzyme E2 M antibody, NEDD8-conjugating enzyme antibody, ubiquitin conjugating enzyme E2M S homeolog antibody, ube2m antibody, LOC692934 antibody, UBE2M antibody, Ube2m antibody, ube2m.S antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.

Molecular Weight: 21 kDa (MW of target protein)