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Manic Fringe antibody (C-Term)

MFNG Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN633865
  • Target See all Manic Fringe (MFNG) Antibodies
    Manic Fringe (MFNG) (MFNG)
    Binding Specificity
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 27
    • 26
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 40
    • 4
    • 1
    Rabbit
    Clonality
    • 44
    • 1
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Manic Fringe antibody is un-conjugated
    Application
    • 19
    • 14
    • 14
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    MFNG antibody was raised against the C terminal of MFNG
    Purification
    Affinity purified
    Immunogen
    MFNG antibody was raised using the C terminal of MFNG corresponding to a region with amino acids QLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYP
    Top Product
    Discover our top product MFNG Primary Antibody
  • Application Notes
    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    MFNG Blocking Peptide, catalog no. 33R-7632, is also available for use as a blocking control in assays to test for specificity of this MFNG antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MFNG antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    Manic Fringe (MFNG) (MFNG)
    Alternative Name
    MFNG (MFNG Products)
    Synonyms
    AW546563 antibody, MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, MFNG antibody, Mfng antibody
    Background
    MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
    Molecular Weight
    36 kDa (MW of target protein)
    Pathways
    Notch Signaling
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