NKX3-1 antibody (AA 21-37)

Catalog No. ABIN636308

Product Details anti-NKX3-1 Antibody

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Binding Specificity: AA 21-37

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogen: NKX3.1 antibody was raised in rabbit using AA 21-37 (TPSKPLTSFLIQDILRD) of human NKX3.1 as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:1,000-1:5,000
Optimal conditions should be determined by the investigator.

Comment:

The immunogen sequence is highly conserved in Mouse, and rat homologs.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS, with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Alternative Name: NKX3.1 (NKX3-1 Products)

Synonyms: Xbagpipe antibody, Xbap antibody, bagpipe antibody, koza antibody, nkx3-1 antibody, nkx3.1 antibody, si:ch211-67o1.2 antibody, nkx3a antibody, MGC53041 antibody, MGC97890 antibody, Bax antibody, NKX3.1 antibody, NKX3A antibody, Nkx-3.1 antibody, BAPX2 antibody, NKX3 antibody, NK3 homeobox 1 L homeolog antibody, NK3 homeobox 1 antibody, NK-3 transcription factor, locus 1 (Drosophila) antibody, nkx3-1.L antibody, NKX3-1 antibody, nkx3-1 antibody, Nkx3-1 antibody

Background: NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and tumorigenesis. NKX3.1 expression is dramatically down-regulated in testicular cancer of germ cell origin.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus