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IL12 antibody

This Goat Polyclonal antibody specifically detects IL12 in ELISA, WB and Inhibition. It exhibits reactivity toward Human.
Catalog No. ABIN636601

Quick Overview for IL12 antibody (ABIN636601)

Target

See all IL12 Antibodies
IL12 (Interleukin 12 (IL12))

Reactivity

  • 49
  • 20
  • 16
  • 7
  • 4
  • 2
  • 1
  • 1
Human

Host

  • 33
  • 27
  • 16
  • 12
  • 2
Goat

Clonality

  • 50
  • 37
Polyclonal

Conjugate

  • 39
  • 14
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This IL12 antibody is un-conjugated

Application

  • 71
  • 56
  • 26
  • 26
  • 14
  • 11
  • 10
  • 8
  • 8
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)
  • Purification

    Purified

    Immunogen

    IL12 antibody was raised in goat using highly pure recombinant human IL12 human as the immunogen.
  • Application Notes

    ELISA: 0.5-2 µg/mL, Inhibition: 0.012-0.02 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    Lot specific

    Buffer

    Lyophilized from PBS, pH 7.2.

    Handling Advice

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Target

    IL12 (Interleukin 12 (IL12))

    Alternative Name

    IL12

    Background

    IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells.

    Molecular Weight

    75 kDa (predicted detection band MW)

    Pathways

    JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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