Neuroserpin antibody

Catalog No. ABIN636686

The Rabbit Polyclonal anti-Neuroserpin antibody is suitable to detect Neuroserpin in samples from Human. It has been validated for WB, ELISA and InhibAb.

Quick Overview for Neuroserpin antibody (ABIN636686)

Target: Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroserpin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Product Details anti-Neuroserpin Antibody

Purification: Purified

Immunogen: Neuroserpin antibody was raised in rabbit using highly pure recombinant human neuroserpin as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for Neuroserpin

Target: Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))

Alternative Name: Neuroserpin

Background: Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala.

Molecular Weight: 44.6 kDa (predicted detection band MW)

Pathways: Regulation of Hormone Metabolic Process