BAI1 antibody

Catalog No. ABIN636927

Product Details anti-BAI1 Antibody

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAI1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogen: BAI1 antibody was raised in rabbit using a synthetic peptide conjugated to KLHd as the immunogen.

Application Details

Application Notes: IHC-P: 20 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for BAI1

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Alternative Name: BAI1 (BAI1 Products)

Synonyms: BAI1 antibody, GDAIF antibody, B830018M07Rik antibody, R75078 antibody, mKIAA4089 antibody, brain-specific angiogenesis inhibitor 1 antibody, adhesion G protein-coupled receptor B1 antibody, BAI1 antibody, ADGRB1 antibody, LOC100228084 antibody, Adgrb1 antibody

Background: Brain-specific angiogenesis inhibitor 1 is a protein that in humans is encoded by the BAI1 gene. Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators.

Pathways: p53 Signaling