Recombinant Bcl-2 antibody

Catalog No. ABIN6383841

The Mouse Monoclonal anti-Bcl-2 antibody is suitable to detect Bcl-2 in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant Bcl-2 antibody (ABIN6383841)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RBCL2-796

Product Details anti-Bcl-2 Antibody

Purpose: BCL2

Purification: By Protein G from bioreactor concentrate

Immunogen: Recombinant full-length human BCL2 protein

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Jurkat, K562, HL-60, HeLa, tonsil, spleen, follicular lymphoma

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg IgG/mL in PBS, 0.05 % azide

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage Comment: For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: BCL2

Background: Apoptosis regulator BCL-2, B-cell CLL/lymphoma-2, Bcl-2, PPP1R50

Gene ID: 596

UniProt: P10415

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling