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IFNA antibody

The Mouse Monoclonal anti-IFNA antibody has been validated for WB and ELISA. It is suitable to detect IFNA in samples from Chicken.
Catalog No. ABIN639854

Quick Overview for IFNA antibody (ABIN639854)

Target

See all IFNA Antibodies
IFNA (Interferon alpha (IFNA))

Reactivity

  • 51
  • 20
  • 14
  • 13
  • 12
  • 9
  • 8
  • 7
  • 5
  • 5
  • 3
  • 2
  • 1
Chicken

Host

  • 82
  • 54
  • 6
  • 5
  • 1
Mouse

Clonality

  • 89
  • 58
Monoclonal

Conjugate

  • 104
  • 20
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFNA antibody is un-conjugated

Application

  • 138
  • 96
  • 80
  • 77
  • 28
  • 13
  • 13
  • 13
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • Purpose

    Mouse Anti-Chicken IFN-alpha

    Specificity

    DS-MB-01578 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFN I) or Type II Interferon (IFN II). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. DS-MB-01578 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.

    Characteristics

    Cytokines/Chemokines/Growth Factors/Receptors

    Purification

    Purified

    Immunogen

    Recombinant chicken Interferon alpha

    Isotype

    IgG1
  • Application Notes

    ELISA, Western Blotting

    Restrictions

    For Research Use only
  • Concentration

    IgG concentration 0.5 mg/ml

    Buffer

    Phosphate buffered saline

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    IFNA (Interferon alpha (IFNA))

    Alternative Name

    Interferon-alpha (IFNa)

    Pathways

    JAK-STAT Signaling, TLR Signaling, Hepatitis C, Inflammasome
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