IFNA antibody

Catalog No. ABIN639854

The Mouse Monoclonal anti-IFNA antibody is suitable to detect IFNA in samples from Chicken. It has been validated for WB and ELISA.

Quick Overview for IFNA antibody (ABIN639854)

Target: IFNA (Interferon alpha (IFNA))

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IFNA Antibody

Purpose: Mouse Anti-Chicken IFN-alpha

Specificity: DS-MB-01578 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFN I) or Type II Interferon (IFN II). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. DS-MB-01578 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.

Characteristics: Cytokines/Chemokines/Growth Factors/Receptors

Purification: Purified

Immunogen: Recombinant chicken Interferon alpha

Isotype: IgG1

Application Details

Application Notes: ELISA, Western Blotting

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 0.5 mg/ml

Buffer: Phosphate buffered saline

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for IFNA

Target: IFNA (Interferon alpha (IFNA))

Alternative Name: Interferon-alpha (IFNa)

Pathways: JAK-STAT Signaling, TLR Signaling, Hepatitis C, Inflammasome