GADD45A antibody (C-Term)

Catalog No. ABIN650724

Cited in 1 publication. The Rabbit Polyclonal anti-GADD45A antibody (Clone RB16521) (ABIN650724) specifically detects GADD45A in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for GADD45A antibody (C-Term) (ABIN650724)

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB16521

Product Details anti-GADD45A Antibody

Binding Specificity: AA 133-165, C-Term

Predicted Reactivity: B, Ha, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GADD45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the C-terminal region of human GADD45A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-GADD45A antibody (ABIN650724)

Wu, Boonmars, Nagano, Boonjaraspinyo, Srinontong, Ratasuwan, Narong, Nielsen, Maekawa: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A

Background: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.

Molecular Weight: 18336

Gene ID: 1647

NCBI Accession: NP_001186670, NP_001186671, NP_001915

UniProt: P24522

Pathways: p53 Signaling, Cell Division Cycle