TOX3 antibody (AA 214-242)

Catalog No. ABIN651009

This anti-TOX3 antibody is a Rabbit Polyclonal antibody detecting TOX3 in FACS, WB and IHC (p). Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for TOX3 antibody (AA 214-242) (ABIN651009)

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOX3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24743

Product Details anti-TOX3 Antibody

Binding Specificity: AA 214-242

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TOX3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-TOX3 antibody (ABIN651009)

Han, Yue, Yang, Jian, Ma, Liu: "TOX3 protein expression is correlated with pathological characteristics in breast cancer." in: Oncology letters, Vol. 11, Issue 3, pp. 1762-1768, (2016) (PubMed).

Target Details for TOX3

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Alternative Name: TOX3

Background: TOX3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.

Molecular Weight: 63342

Gene ID: 27324

NCBI Accession: NP_001073899, NP_001139660

UniProt: O15405

Pathways: Chromatin Binding