Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TOX3 antibody (AA 251-389)

TOX3 Reactivity: Human WB, ELISA, Coat Host: Mouse Monoclonal TOX3-1124 unconjugated
Catalog No. ABIN6938637
  • Target See all TOX3 Antibodies
    TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
    Binding Specificity
    • 22
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    AA 251-389
    Reactivity
    • 46
    • 8
    Human
    Host
    • 25
    • 20
    • 1
    Mouse
    Clonality
    • 25
    • 21
    Monoclonal
    Conjugate
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TOX3 antibody is un-conjugated
    Application
    • 33
    • 30
    • 22
    • 20
    • 17
    • 7
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    Specificity
    It recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary)
    Clone
    TOX3-1124
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TOX3 Primary Antibody
  • Application Notes

    Known_Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: SH-SY5Y, MDA-MB-435 cells. Brain or breast or gastric Carcinoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
    Alternative Name
    TOX3 (TOX3 Products)
    Synonyms
    TNRC9 antibody, cagf9 antibody, tnrc9 antibody, CAGF9 antibody, 500-9 antibody, BC052044 antibody, C230068E13 antibody, Tnrc9 antibody, TOX high mobility group box family member 3 antibody, TOX3 antibody, tox3 antibody, Tox3 antibody
    Background
    TOX3, CAG trinucleotide repeat-containing gene F9 protein, CAGF9, TOX high mobility group box family member 3, Trinucleotide repeat containing 9 (TNRC9),TOX3 / TNRC9
    Cellular localisation: Cytoplasmic & Nuclear
    Molecular Weight
    63kDa
    Gene ID
    27324, 460789
    UniProt
    O15405
    Pathways
    Chromatin Binding
You are here:
Support