TOX3 antibody (AA 8-305)

Catalog No. ABIN7172313

The Rabbit Polyclonal anti-TOX3 antibody is suitable to detect TOX3 in samples from Human. It has been validated for WB, ELISA, IF and IHC.

Quick Overview for TOX3 antibody (AA 8-305) (ABIN7172313)

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-TOX3 Antibody

Binding Specificity: AA 8-305

Purpose: TOX3 Antibody

Cross-Reactivity: Mouse

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human TOX high mobility group box family member 3 protein (8-305AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TOX3

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Alternative Name: TOX3

Background:

Background: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.

Aliases: BC052044 antibody, C230068E13 antibody, CAG trinucleotide repeat-containing gene F9 protein antibody, CAGF9 antibody, TNRC9 antibody, TOX high mobility group box family member 3 antibody, TOX3 antibody, TOX3_HUMAN antibody, Trinucleotide repeat containing 9 antibody, Trinucleotide repeat containing gene 9 protein antibody

UniProt: O15405

Pathways: Chromatin Binding