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VEGFR2/CD309 antibody (Tyr1175)

This anti-VEGFR2/CD309 antibody is a Rabbit Polyclonal antibody detecting VEGFR2/CD309 in WB and FACS. Suitable for Human and Mouse.
Catalog No. ABIN652371

Quick Overview for VEGFR2/CD309 antibody (Tyr1175) (ABIN652371)

Target

See all VEGFR2/CD309 (VEGFR2) Antibodies
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity

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Human, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This VEGFR2/CD309 antibody is un-conjugated

Application

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Western Blotting (WB), Flow Cytometry (FACS)

Clone

RB25842
  • Binding Specificity

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    AA 1153-1182, Tyr1175

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This KDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1153-1182 amino acids from human KDR.

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:1000. FC: 1:10~50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    Alternative Name

    KDR

    Background

    KDR is a major growth factor for endothelial cells. This protein encodes one of the two receptors of the KDR. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..

    Molecular Weight

    151527

    Gene ID

    3791

    NCBI Accession

    NP_002244

    UniProt

    P35968

    Pathways

    RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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