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FAK antibody (C-Term)

This anti-FAK antibody is a Rabbit Polyclonal antibody detecting FAK in WB, IF, FACS and IHC (p). Suitable for Human. This Primary Antibody has been cited in 1 publication.
Catalog No. ABIN652554

Quick Overview for FAK antibody (C-Term) (ABIN652554)

Target

See all FAK (PTK2) Antibodies
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This FAK antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB20776
  • Binding Specificity

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    AA 821-848, C-Term

    Predicted Reactivity

    M, Rat

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-848 amino acids from the C-terminal region of human PTK2.

    Isotype

    Ig Fraction
  • Application Notes

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Ma, He, Zhang, Fei, Niu, Wang, Ding, Xu, Chen, Zhu: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).

  • Target

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    Alternative Name

    PTK2

    Background

    PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

    Molecular Weight

    119233

    Gene ID

    5747

    NCBI Accession

    NP_001186578, NP_722560

    UniProt

    Q05397

    Pathways

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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