Recombinant UPK1A antibody (AA 100-200)

Catalog No. ABIN7864274

This Rabbit Monoclonal antibody specifically detects UPK1A in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant UPK1A antibody (AA 100-200) (ABIN7864274)

Target: UPK1A (Uroplakin 1a (UPK1A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: UPK1A-8704R

Product Details anti-UPK1A Antibody

Binding Specificity: AA 100-200

Purpose: Recombinant Uroplakin 1A (Urothelial Differentiation Marker) Antibody

Specificity: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.Ç 79oΩ

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 100-200) of human Uroplakin 1A (UPK1A) protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: Uroplakin 1A

Background:

UP1A, UPIA, UPKA, TSPAN21

Urinary Bladder

Molecular Weight: 29kDa

Gene ID: 11045, 159309

UniProt: O00322