MEF2A antibody (AA 453-479)

Catalog No. ABIN2842748

This Rabbit Polyclonal antibody specifically detects MEF2A in WB, IF and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for MEF2A antibody (AA 453-479) (ABIN2842748)

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21291

Product Details anti-MEF2A Antibody

Binding Specificity: AA 453-479

Predicted Reactivity: B, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MEF2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-479 amino acids from the Central region of human MEF2A.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Alternative Name: MEF2A

Background: MEF2A is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this protein could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1).

Molecular Weight: 54811

Gene ID: 4205

NCBI Accession: NP_001124398, NP_001124399, NP_001124400, NP_001165365, NP_005578

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades