This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MIER2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human MIER2.
KIAA1193 antibody, Mi-er2 antibody, 2700087H15Rik antibody, mKIAA1193 antibody, RGD1307278 antibody, mesoderm induction early response 1, family member 2 S homeolog antibody, mesoderm induction early response 1, family member 2 antibody, MIER family member 2 antibody, mier2.S antibody, mier2 antibody, MIER2 antibody, Mier2 antibody
Background
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity).