Cyclin G1 antibody (C-Term)

Catalog No. ABIN655159

This Rabbit Polyclonal antibody specifically detects Cyclin G1 in WB and FACS. It exhibits reactivity toward Mouseand has been mentioned in 1 publication.

Quick Overview for Cyclin G1 antibody (C-Term) (ABIN655159)

Target: Cyclin G1 (CCNG1)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin G1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB14997

Product Details anti-Cyclin G1 Antibody

Binding Specificity: AA 243-272, C-Term

Predicted Reactivity: Pig

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CCNG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the C-terminal region of human CCNG1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Cyclin G1 antibody (ABIN655159)

Selcuklu, Donoghue, Rehmet, de Souza Gomes, Fort, Kovvuru, Muniyappa, Kerin, Enright, Spillane: "MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells." in: The Journal of biological chemistry, Vol. 287, Issue 35, pp. 29516-28, (2012) (PubMed).

Target Details for Cyclin G1

Target: Cyclin G1 (CCNG1)

Alternative Name: CCNG1

Background: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].

Molecular Weight: 34074

Gene ID: 900

NCBI Accession: NP_004051, NP_954854

UniProt: P51959

Pathways: p53 Signaling