DUOX2 antibody (AA 513-542)

Catalog No. ABIN655174

This Rabbit Polyclonal antibody specifically detects DUOX2 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for DUOX2 antibody (AA 513-542) (ABIN655174)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB19278

Product Details anti-DUOX2 Antibody

Binding Specificity: AA 513-542

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DUOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Alternative Name: DUOX2

Background: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

Molecular Weight: 175364

Gene ID: 50506

NCBI Accession: NP_054799

UniProt: Q9NRD8

Pathways: Thyroid Hormone Synthesis