DUOX2 antibody (AA 63-403)

Catalog No. ABIN7602208

The Rabbit Polyclonal anti-DUOX2 antibody is suitable to detect DUOX2 in samples from Rat and Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for DUOX2 antibody (AA 63-403) (ABIN7602208)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-DUOX2 Antibody

Binding Specificity: AA 63-403

Purpose: Anti-Duox2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Duox2 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Duox2 recombinant protein (Position: A63-D403).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Alternative Name: Duox2

Background:

Background: Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

Gene Full Name: dual oxidase 2

Molecular Weight: 175 kDa

Gene ID: 214593

UniProt: B7ZWM4

Pathways: Thyroid Hormone Synthesis