DUOX2 antibody (Middle Region)

Catalog No. ABIN951993

The Rabbit Polyclonal anti-DUOX2 antibody (ABIN951993) specifically detects DUOX2 in WB, FACS and EIA. The antibody is reactive with Human samples.

Quick Overview for DUOX2 antibody (Middle Region) (ABIN951993)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-DUOX2 Antibody

Binding Specificity: AA 520-550, Middle Region

Specificity: This antibody recognizes Human Dual oxidase 2 (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 520-550 amino acids from the Central region of human DUOX2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Alternative Name: Dual Oxidase 2

Background: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.Synonyms: LNOX2, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, THOX2, Thyroid oxidase 2, p138 thyroid oxidase

Molecular Weight: 175364 Da

Gene ID: 50506

NCBI Accession: NP_054799

Pathways: Thyroid Hormone Synthesis