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NOD1 antibody (C-Term)

NOD1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB29527 unconjugated
Catalog No. ABIN655750
  • Target See all NOD1 Antibodies
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    Binding Specificity
    • 11
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 923-951, C-Term
    Reactivity
    • 42
    • 20
    • 14
    Human, Mouse
    Host
    • 45
    • 3
    • 1
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOD1 antibody is un-conjugated
    Application
    • 40
    • 23
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 923-951 amino acids from the C-terminal region of human NOD1.
    Clone
    RB29527
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NOD1 Primary Antibody
  • Application Notes
    WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    Alternative Name
    NOD1 (NOD1 Products)
    Synonyms
    CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
    Background
    This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.
    Molecular Weight
    107691
    Gene ID
    10392
    NCBI Accession
    NP_006083
    UniProt
    Q9Y239
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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