ATRX antibody (C-Term)

Catalog No. ABIN655910

Product Details anti-ATRX Antibody

Target: ATRX (helicase 2, X-linked (ATRX))

Binding Specificity: AA 634-663, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATRX antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Predicted Reactivity: C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAD54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 634-663 amino acids from the C-terminal region of human RAD54.

Clone: RB20635

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ATRX

Target: ATRX (helicase 2, X-linked (ATRX))

Alternative Name: RAD54 (ATRX Products)

Synonyms: ATR2 antibody, JMS antibody, MRXHF1 antibody, RAD54 antibody, RAD54L antibody, SFM1 antibody, SHS antibody, XH2 antibody, XNP antibody, ZNF-HX antibody, 4833408C14Rik antibody, AI447451 antibody, DXHXS6677E antibody, HP1-BP38 antibody, Hp1bp2 antibody, Hp1bp38 antibody, MRXS3 antibody, Rad54 antibody, Xnp antibody, atrx antibody, rad54 antibody, atrxl antibody, wu:fb26e12 antibody, wu:fb52h08 antibody, wu:fb72g09 antibody, wu:fb94e07 antibody, zgc:66223 antibody, ATRX, chromatin remodeler antibody, alpha thalassemia/mental retardation syndrome X-linked L homeolog antibody, alpha thalassemia/mental retardation syndrome X-linked homolog (human) antibody, ATRX antibody, Atrx antibody, atrx.L antibody, atrx antibody

Background: The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.

Molecular Weight: 84352

Gene ID: 8438

NCBI Accession: NP_001136020, NP_003570

UniProt: Q92698