SMAD6 antibody

Catalog No. ABIN6566617

This anti-SMAD6 antibody is a Rabbit Polyclonal antibody detecting SMAD6 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for SMAD6 antibody (ABIN6566617)

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMAD6 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SMAD6

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMAD6

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Alternative Name: SMAD6

Background:

Synonyms: hSMAD6,MAD homolog 6,MADH6,MADH7,Mothers against decapentaplegic homolog 6,Mothers against DPP homolog 6,SMAD 6,SMAD family member 6,SMAD mothers against DPP homolog 6,Smad6,SMAD6

Background: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.

Molecular Weight:

Observed_MW: 48kDa

Calculated_MW: 26kDa/35kDa/53kDa

Gene ID: 4091

UniProt: O43541

Pathways: Chromatin Binding