CABLES1 antibody

Catalog No. ABIN6566881

Product Details anti-CABLES1 Antibody

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABLES1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CABLES1

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CABLES1

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Alternative Name: CABLES1 (CABLES1 Products)

Synonyms: CABLES1 antibody, si:dkey-2p18.3 antibody, CABL1 antibody, CABLES antibody, HsT2563 antibody, IK3-1 antibody, Cables antibody, ik3-1 antibody, Cdk5 and Abl enzyme substrate 1 antibody, CDK5 and Abl enzyme substrate 1 antibody, CABLES1 antibody, cables1 antibody, CpipJ_CPIJ019832 antibody, Cables1 antibody

Background:

Synonyms: CABL1,CABLES,Cables1,Cdk5 and Abl enzyme substrate 1,CDK5 and ABL1 enzyme substrate 1,FLJ35924,HsT2563,IK3 1,Ik3-1,Interactor with CDK3 1

Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 68kDa

Calculated_MW: 15kDa/34kDa/41kDa/67kDa

Gene ID: 91768

UniProt: Q8TDN4