GPSM2 antibody (G-Protein Signaling Modulator 2)

Details for Product anti-GPSM2 Antibody No. ABIN6566981
Antigen
Reactivity
Human, Mouse (Murine)
31
18
16
4
4
4
4
3
3
2
1
1
Host
Rabbit
24
7
Clonality
Polyclonal
Conjugate
This GPSM2 antibody is un-conjugated
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
26
15
9
3
2
1
Options
Immunogen Recombinant protein of human GPSM2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name GPSM2 (GPSM2 Antibody Abstract)
Background

Synonyms: DFNB82,G protein signalling modulator 2 (AGS3 like C. elegans),G protein signalling modulator 2,G-protein-signaling modulator 2,Gpsm2,GPSM2,HGNC:29501,LGN,LGN protein,Mosaic protein LGN,Pins

Background: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.

Molecular Weight

Observed_MW: 77kDa

Calculated_MW: 76kDa

Gene ID 29899
UniProt P81274
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-G-Protein Signaling Modulator 2 (GPSM2) antibody (ABIN6566981) Western blot analysis of extracts of various cell lines, using GPSM2 antibody.