PPP3CA antibody

Catalog No. ABIN6567007

The Rabbit Polyclonal anti-PPP3CA antibody is suitable to detect PPP3CA in samples from Human and Mouse. It has been validated for IF.

Quick Overview for PPP3CA antibody (ABIN6567007)

Target: PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CA antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-PPP3CA Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PPP3CA (NP_001124163.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPP3CA

Target: PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))

Alternative Name: PPP3CA

Background: Protein phosphatase 3, catalytic subunit, alpha isozymeis aproteinthat in humans is encoded by thePPP3CAgene. Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.

Molecular Weight:

Observed_MW: 57kDa

Calculated_MW: 31kDa/51kDa/52kDa/57kDa/58kDa

Gene ID: 5530

UniProt: Q08209

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling