CD3D antibody
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- Target See all CD3D Antibodies
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD3D antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CD3D (NP_000723.1).
- Isotype
- IgG
- Top Product
- Discover our top product CD3D Primary Antibody
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- Application Notes
- IHC 1:50-1:100 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
- Alternative Name
- CD3D (CD3D Products)
- Synonyms
- CD3-DELTA antibody, T3D antibody, CD3 antibody, T3d antibody, CD3d molecule antibody, CD3 antigen, delta polypeptide antibody, CD3D antibody, Cd3d antibody
- Background
- The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
- Molecular Weight
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Observed_MW: 19kDa
Calculated_MW: 14kDa/18kDa
- Gene ID
- 915
- UniProt
- P04234
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events
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