GCN2 antibody
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- Target See all GCN2 (EIF2AK4) Antibodies
- GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GCN2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human EIF2AK4
- Isotype
- IgG
- Top Product
- Discover our top product EIF2AK4 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))
- Alternative Name
- EIF2AK4 (EIF2AK4 Products)
- Synonyms
- EIF2AK4 antibody, Gcn2-like antibody, GCN2 antibody, 2610011M03 antibody, MGCN2 antibody, eukaryotic translation initiation factor 2 alpha kinase 4 antibody, eukaryotic translation initiation factor 2-alpha kinase 4 antibody, eIF-2-alpha kinase GCN2 antibody, EIF2AK4 antibody, LOC579979 antibody, LOC100187226 antibody, eif2ak4 antibody, Eif2ak4 antibody
- Background
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Synonyms: E2AK4,Eif2ak4,Eukaryotic Translation Initiation Factor 2 alpha kinase 4,Eukaryotic translation initiation factor 2-alpha kinase 4,GCN2,GCN2 eIF2alpha kinase,GCN2 like protein,GCN2-like protein,KIAA1338,MGCN2
Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
- Molecular Weight
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Observed_MW: 187kDa
Calculated_MW: 69kDa/183kDa/186kDa
- Gene ID
- 440275
- UniProt
- Q9P2K8
- Pathways
- ER-Nucleus Signaling, Hepatitis C
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