SNX13 antibody

Catalog No. ABIN6567653

Product Details anti-SNX13 Antibody

Target: SNX13 (Sorting Nexin 13 (SNX13))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX13 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SNX13 (NP_055947.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNX13

Target: SNX13 (Sorting Nexin 13 (SNX13))

Alternative Name: SNX13 (SNX13 Products)

Synonyms: MGC142644 antibody, DKFZp469H181 antibody, Rgs-px1 antibody, mKIAA0713 antibody, RGS-PX1 antibody, sorting nexin 13 antibody, SNX13 antibody, Snx13 antibody

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Molecular Weight:

Observed_MW: 112kDa

Calculated_MW: 110kDa/112kDa

Gene ID: 23161

UniProt: Q9Y5W8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling