TAPBP antibody

Catalog No. ABIN6567907

The Rabbit Polyclonal anti-TAPBP antibody has been validated for WB, IHC and IF. It is suitable to detect TAPBP in samples from Human, Mouse and Rat.

Quick Overview for TAPBP antibody (ABIN6567907)

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAPBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TAPBP Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human TAPBP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TAPBP

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Alternative Name: TAPBP

Background:

Synonyms: NGS 17,NGS-17,NGS17,TAP associated protein ,TAP binding protein ,TAP binding protein (tapasin),TAP BP,TAP-associated protein,TAP-binding protein,TAPA,Tapasin,TAPBP,TPN,TPSN,TPSN

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 50kDa

Calculated_MW: 38kDa/43kDa/47kDa/53kDa

Gene ID: 6892

UniProt: O15533