FBXL5 antibody

Catalog No. ABIN6569998

Product Details anti-FBXL5 Antibody

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human FBXL5 (NP_036293.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXL5

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Alternative Name: FBXL5 (FBXL5 Products)

Synonyms: fbxl5 antibody, MGC53238 antibody, FBXL5 antibody, FBL4 antibody, FBL5 antibody, FLR1 antibody, Fbl4 antibody, Fir4 antibody, wu:fb52d06 antibody, F-box and leucine rich repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 S homeolog antibody, F-box and leucine-rich repeat protein 5 L homeolog antibody, F-box and leucine-rich repeat protein 5 antibody, FBXL5 antibody, fbxl5.S antibody, fbxl5.L antibody, fbxl5 antibody, Fbxl5 antibody

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.

Molecular Weight:

Observed_MW: 79kDa

Calculated_MW: 76kDa/78kDa

Gene ID: 26234

UniProt: Q9UKA1

Pathways: Transition Metal Ion Homeostasis