Adracalin antibody

Catalog No. ABIN6570435

Product Details anti-Adracalin Antibody

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adracalin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human AAAS

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Adracalin

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Alternative Name: AAAS (AAAS Products)

Synonyms: zgc:85873 antibody, aladin antibody, Aladin antibody, AAA antibody, AAASb antibody, ADRACALA antibody, ADRACALIN antibody, ALADIN antibody, D030041N15Rik antibody, GL003 antibody, aladin WD repeat nucleoporin antibody, achalasia, adrenocortical insufficiency, alacrimia antibody, aladin WD repeat nucleoporin L homeolog antibody, Aaas antibody, aaas antibody, aaas.L antibody, AAAS antibody

Background:

Synonyms: AAA,AAAS,AAASb,Achalasia adrenocortical insufficiency alacrimia (Allgrove triple A),Achalasia adrenocortical insufficiency alacrimia,ADRACALA,ADRACALIN,Aladin,Allgrove triple A,DKFZp586G1624,GL003

Background: The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 60kDa

Calculated_MW: 55kDa/59kDa

Gene ID: 8086

UniProt: Q9NRG9