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Melanophilin antibody

MLPH Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6570602
  • Target See all Melanophilin (MLPH) Antibodies
    Melanophilin (MLPH)
    Reactivity
    • 36
    • 9
    • 3
    • 1
    Human, Mouse, Rat
    Host
    • 36
    • 4
    • 1
    Rabbit
    Clonality
    • 39
    • 2
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Melanophilin antibody is un-conjugated
    Application
    • 31
    • 21
    • 21
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MLPH (NP_077006.1).
    Isotype
    IgG
    Top Product
    Discover our top product MLPH Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Melanophilin (MLPH)
    Alternative Name
    MLPH (MLPH Products)
    Synonyms
    MGC155106 antibody, LOC100222096 antibody, 2210418F23Rik antibody, 5031433I09Rik antibody, AW228792 antibody, D1Wsu84e antibody, Slac-2a antibody, l(1)-3Rk antibody, l1Rk3 antibody, ln antibody, SLAC2-A antibody, melanophilin antibody, MLPH antibody, mlph antibody, Mlph antibody
    Background
    This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 68kDa

    Calculated_MW: 50kDa/52kDa/60kDa/62kDa/65kDa

    Gene ID
    79083
    UniProt
    Q9BV36
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