ISCU antibody

Catalog No. ABIN6570907

Product Details anti-ISCU Antibody

Target: ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ISCU antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ISCU

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ISCU

Target: ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

Alternative Name: ISCU (ISCU Products)

Synonyms: nifun antibody, zC191D15.3 antibody, si:ch211-191d15.3 antibody, 2310020H20Rik antibody, HML antibody, ISU2 antibody, NIFU antibody, NIFUN antibody, hnifU antibody, RGD1309562 antibody, AA407971 antibody, Nifu antibody, Nifun antibody, iron-sulfur cluster assembly enzyme ISCU, mitochondrial antibody, iron-sulfur cluster assembly enzyme antibody, iron-sulfur cluster assembly enzyme a antibody, LOC409130 antibody, ISCU antibody, iscua antibody, Iscu antibody

Background:

Synonyms: 2310020H20Rik,HML,hnifU,Iron sulfur cluster assembly enzyme ISCU mitochondrial,Iron sulfur cluster scaffold homolog (E. coli),Iron sulfur cluster scaffold homolog,Iron-sulfur cluster assembly enzyme ISCU,Iscu,IscU iron sulfur cluster scaffold homolog,ISCU,ISU2,MGC74517,mitochondrial,NIFU,NifU like N terminal domain containing,NifU like N terminal domain containing protein,NifU like protein,NifU-like N-terminal domain-containing protein,NifU-like protein,NIFUN,Nitrogen fixation cluster like,OTTHUMP00000238760,OTTHUMP00000238761,OTTHUMP00000238762,OTTHUMP00000238764,OTTHUMP00000238765

Background: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

Molecular Weight:

Observed_MW: 18kDa

Calculated_MW: 15kDa/17kDa

Gene ID: 23479

UniProt: Q9H1K1