CDC16 antibody

Catalog No. ABIN6570985

Product Details anti-CDC16 Antibody

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CDC16 (NP_003894.3).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDC16

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Alternative Name: CDC16 (CDC16 Products)

Synonyms: zgc:123264 antibody, F9K20.19 antibody, F9K20_19 antibody, anaphase promoting complex 6 antibody, 2700071J12Rik antibody, 2810431D22Rik antibody, APC6 antibody, ANAPC6 antibody, CUT9 antibody, cell division cycle 16 antibody, cell division cycle 16 L homeolog antibody, cell division cycle 16 homolog (S. cerevisiae) antibody, cell division cycle protein 16 homolog antibody, anaphase promoting complex 6 antibody, CDC16 cell division cycle 16 antibody, CDC16 antibody, cdc16.L antibody, cdc16 antibody, LOC100434328 antibody, APC6 antibody, Cdc16 antibody

Background: The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain, a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified.

Molecular Weight:

Observed_MW: 72kDa

Calculated_MW: 60kDa/65kDa/71kDa

Gene ID: 8881

UniProt: Q13042

Pathways: Regulation of Actin Filament Polymerization