Transportin 1 antibody

Catalog No. ABIN6571982

The Rabbit Polyclonal anti-Transportin 1 antibody is suitable to detect Transportin 1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Transportin 1 antibody (ABIN6571982)

Target: Transportin 1 (TNPO1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Transportin 1 Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human TNPO1 (NP_002261.3).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Transportin 1

Target: Transportin 1 (TNPO1)

Alternative Name: TNPO1

Background: This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

Molecular Weight:

Observed_MW: 95kDa, 102kDa

Calculated_MW: 96kDa/101kDa/102kDa

Gene ID: 3842

UniProt: Q92973

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events