ANGPTL4 antibody (AA 301-350)

Catalog No. ABIN6579282

The Rabbit Polyclonal anti-ANGPTL4 antibody (ABIN6579282) specifically detects ANGPTL4 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ANGPTL4 antibody (AA 301-350) (ABIN6579282)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ANGPTL4 Antibody

Binding Specificity: AA 301-350

Purpose: Angptl4 Antibody

Specificity: Angptl4 Polyclonal Antibody detects endogenous levels of Angptl4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ANGPTL4. AA range:301-350

Isotype: IgG

Application Details

Application Notes: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4

Background:

Synonyms: ANGPTL4, ARP4, HFARP, PGAR, PP1158, PSEC0166, Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP

Background: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013],

Gene Name: ANGPTL4

Protein Name: Angiopoietin-related protein 4

Molecular Weight: 45 kDa

Gene ID: 51129

OMIM: 605910

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha