Cullin 4B antibody (AA 711-760)

Catalog No. ABIN6579301

This Rabbit Polyclonal antibody specifically detects Cullin 4B in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Cullin 4B antibody (AA 711-760) (ABIN6579301)

Target: Cullin 4B (CUL4B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Cullin 4B Antibody

Binding Specificity: AA 711-760

Purpose: CUL-4B Antibody

Specificity: CUL-4B Polyclonal Antibody detects endogenous levels of CUL-4B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CUL4B. AA range:711-760

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cullin 4B

Target: Cullin 4B (CUL4B)

Alternative Name: CUL4B

Background:

Synonyms: CUL4B, KIAA0695, Cullin-4B, CUL-4B

Background: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: CUL4B

Protein Name: Cullin-4B

Molecular Weight: 85-110 kDa

Gene ID: 8450

OMIM: 300304

UniProt: Q13620