IL-1 beta antibody (AA 181-230)

Catalog No. ABIN6579326

This Rabbit Polyclonal antibody specifically detects IL-1 beta in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IL-1 beta antibody (AA 181-230) (ABIN6579326)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-1 beta Antibody

Binding Specificity: AA 181-230

Specificity:

IL1B Antibody detects endogenous levels of IL1B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL1B.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL1B

Background:

Synonyms: IL1B, IL1F2, Interleukin-1 beta, IL-1 beta, Catabolin

NCBI Gene Symbol: IL1B

Molecular Weight: 17 kDa

Gene ID: 3553

OMIM: 147720

UniProt: P01584

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome