LAMC2 antibody (AA 1021-1070)

Catalog No. ABIN6579368

The Rabbit Polyclonal anti-LAMC2 antibody is suitable to detect LAMC2 in samples from Human and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for LAMC2 antibody (AA 1021-1070) (ABIN6579368)

Target: LAMC2 (Laminin, gamma 2 (LAMC2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-LAMC2 Antibody

Binding Specificity: AA 1021-1070

Purpose: Laminin γ-2 Antibody

Specificity: Laminin γ-2 Polyclonal Antibody detects endogenous levels of Laminin γ-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human LAMC2. AA range:1021-1070

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LAMC2

Target: LAMC2 (Laminin, gamma 2 (LAMC2))

Alternative Name: LAMC2

Background:

Synonyms: LAMC2, LAMB2T, LAMNB2, Laminin subunit gamma-2, Cell-scattering factor 140 kDa subunit, CSF 140 kDa subunit, Epiligrin subunit gamma, Kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunitLadsin 140 kDa subunit, Laminin B2t chain, Laminin-5 subunit gamma, Large adhesive scatter factor 140 kDa subunit, Nicein subunit gamma

Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological func

Gene Name: LAMC2

Protein Name: Laminin subunit gamma-2

Molecular Weight: 130 kDa

Gene ID: 3918

UniProt: Q13753