CD226 antibody (AA 71-120)

Catalog No. ABIN6579545

The Rabbit Polyclonal anti-CD226 antibody (ABIN6579545) specifically detects CD226 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CD226 antibody (AA 71-120) (ABIN6579545)

Target: CD226

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD226 Antibody

Binding Specificity: AA 71-120

Purpose: DNAM-1 Antibody

Specificity: DNAM-1 Polyclonal Antibody detects endogenous levels of DNAM-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD226. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: CD226

Background:

Synonyms: CD226, DNAM1, CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226

Background: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Gene Name: CD226

Protein Name: CD226 antigen

Molecular Weight: 38-65 kDa

Gene ID: 10666

OMIM: 605397

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints