Thrombomodulin antibody

Catalog No. ABIN6653774

The Mouse Monoclonal anti-Thrombomodulin antibody is suitable to detect Thrombomodulin in samples from Human and Rabbit. It has been validated for FACS, IHC (p) and IHC (fro).

Quick Overview for Thrombomodulin antibody (ABIN6653774)

Target: Thrombomodulin (THBD)

Reactivity: Human, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: QBEND-40

Product Details anti-Thrombomodulin Antibody

Purification: Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum

Immunogen: Human Endothelium (Thrombomodulin).

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted at -20 °C.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: CD141 / THBD

Background: CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.Synonyms: Fetomodulin, THRM, Thrombomodulin

Gene ID: 9606

UniProt: P07204