Calcineurin alpha antibody
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- Target See all Calcineurin alpha products
- Calcineurin alpha
- Reactivity
- Human, Rat, Cow
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Calcineurin alpha antibody is un-conjugated
- Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Cow (Bovine), Human, Rat (Rattus)
- Cross-Reactivity (Details)
- Cross reactivity with Calcineurin alpha from other sources has not been determined.
- Purification
- Anti-Calcineurin alpha antibody was purified from mouse ascites by protein A chromatography. This product reacts with human, rat, and bovine.
- Immunogen
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Immunogen: Calcineurin alpha antibody was produced in mice by repeated immunizations with bovine brain calcineurin.
Immunogen Type: Other
- Clone
- CC-6
- Isotype
- IgG1
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- Application Notes
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Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-Calcineurin alpha is useful for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~19.3 kDa corresponding to the appropriate cell lysate or extract.
ELISA Dilution: 1:5000
Western Blot Dilution: 0.25-0.5 μg/mL
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
0.01 % (w/v) Sodium Azide - Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- Calcineurin alpha
- Abstract
- Calcineurin alpha Products
- Synonyms
- PPP3CC antibody, protein phosphatase 3 catalytic subunit alpha antibody, PPP3CA antibody
- Background
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Synonyms: CNA2, CNB, CNB1, CALNB1, Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1
Background: Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha (PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast. This antibody is suitable for researchers interested in apoptosis, transcription factors, nuclear receptors, cancer research, Immune Response, cardiovascular disease, MAK Kinase Signaling, and AKT Signaling.
Gene Name: PPP3R1
- Gene ID
- 5534
- NCBI Accession
- NP_000936
- UniProt
- P63098
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