ICAM1 antibody (AA 201-300)

Catalog No. ABIN670806

This anti-ICAM1 antibody is a Rabbit Polyclonal antibody detecting ICAM1 in WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (cc) and IF (p). Suitable for Human, Mouse, Rat and Rabbit. This Primary Antibody has been cited in 16+ publications.

Quick Overview for ICAM1 antibody (AA 201-300) (ABIN670806)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ICAM1 Antibody

Binding Specificity: AA 201-300

Specificity: KO-Validated

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse ICAM1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ICAM1 antibody (ABIN670806)

Zhang, Hua, Hou, Du, He, Liu, Hu, Yan: "Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway." in: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3344-3354, (2019) (PubMed).

Yang, Cheng, Liu, Liu, Tan, Guan, Guo, Kuang: "Datura Metel L. Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis and Inhibits Inflammatory Cytokines Production through TLR7/8-MyD88-NF-κB-NLRP3 Inflammasome Pathway." in: Molecules (Basel, Switzerland), Vol. 24, Issue 11, (2019) (PubMed).

Kim, Ko, Lee, Kim, Jo, Cho: "Blocking junctional adhesion molecule C promotes the recovery of cisplatin-induced acute kidney injury." in: The Korean journal of internal medicine, Vol. 32, Issue 6, pp. 1053-1061, (2018) (PubMed).

Wang, Li, Liu, Wang, Cao: "Inhibitory effect of Zanthoxylum bungeanum seed oil on ovalbumin‑induced lung inflammation in a murine model of asthma." in: Molecular medicine reports, Vol. 13, Issue 5, pp. 4289-302, (2017) (PubMed).

Tang, Ni, Cai, Ding, Liu, Zhang et al.: "Renoprotective effects of berberine and its potential effect on the expression of β-arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic ..." in: Journal of diabetes, Vol. 8, Issue 5, pp. 693-700, (2016) (PubMed).

Ji, Wang, Li, Qian: "Up-regulation of ICAM-1mRNA and IL-1βmRNA in lung tissues of a rat model of COPD." in: International journal of clinical and experimental medicine, Vol. 8, Issue 11, pp. 21956-63, (2016) (PubMed).

Ji, Wang, Wang, Chen, Li: "Protective effect of Xuebijing injection against acute lung injury induced by left ventricular ischemia/reperfusion in rabbits." in: Experimental and therapeutic medicine, Vol. 12, Issue 1, pp. 51-58, (2016) (PubMed).

Osada-Oka, Shiota, Izumi, Nishiyama, Tanaka, Yamaguchi, Sakurai, Miura, Iwao: "Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 40, Issue 4, pp. 353-360, (2016) (PubMed).

Xiong, Xu, Tan, Han, Tang, Xu, Zeng, Guo: "Glycyrrhizin Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in BALB/c Mice and Inhibits TNF-?-Induced ICAM-1 Expression via NF-?B/MAPK in HaCaT Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 35, Issue 4, pp. 1335-46, (2015) (PubMed).

Chenna Narendra, Chalise, Magnusson, Uppugunduri: "Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141863, (2015) (PubMed).

Park, Regmi, Park, Lee, Chang, Ku, Kim, Kim: "Protective effect of 7-O-succinyl macrolactin A against intestinal inflammation is mediated through PI3-kinase/Akt/mTOR and NF-?B signaling pathways." in: European journal of pharmacology, Vol. 735, pp. 184-92, (2014) (PubMed).

Qiao, Li, Li, Zhu, Huang, Shao, Bai: "Intermedin protects against renal ischemia-reperfusion injury by inhibition of oxidative stress." in: American journal of physiology. Renal physiology, Vol. 304, Issue 1, pp. F112-9, (2013) (PubMed).

Chu, He, Kuang, Ren, Gou: "Celastrol protects kidney against ischemia-reperfusion-induced injury in rats." in: The Journal of surgical research, Vol. 186, Issue 1, pp. 398-407, (2013) (PubMed).

Zhang, Lv, Chen, Zou, Lin, Yang, Guo, Lin: "Effect of mild hypothermia on breast cancer cells adhesion and migration." in: Bioscience trends, Vol. 6, Issue 6, pp. 313-24, (2013) (PubMed).

Wang, Shi, Cui, Bai, He, Shang, Su, Xin, Jing, Zhu: "Preliminary Research of Relationship between Acute Peritonitis and Celiac Primo Vessels." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 569161, (2013) (PubMed).

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM1

Target Type: Viral Protein

Background:

Synonyms: CD54, Ly-47, Icam-1, MALA-2, Intercellular adhesion molecule 1, MyD1, Icam1

Background: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity).

Gene ID: 15894

UniProt: P13597

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling