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CRB1 antibody

CRB1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6719658
  • Target See all CRB1 Antibodies
    CRB1 (Crumbs Homolog 1 (CRB1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 18
    • 1
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRB1 antibody is un-conjugated
    Application
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for CRB1 detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    FRTRDANVII LHAEKEPEFL NISIQDSRLF FQLQ
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for CRB1 detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence of human CRB1 (FRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQ).
    Isotype
    IgG
    Top Product
    Discover our top product CRB1 Primary Antibody
  • Application Notes

    Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL

    Comment

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    CRB1 (Crumbs Homolog 1 (CRB1))
    Alternative Name
    CRB1 (CRB1 Products)
    Synonyms
    CRB1 antibody, si:dkey-114d20.6 antibody, si:dkey-114d20.7 antibody, LCA8 antibody, RP12 antibody, 7530426H14Rik antibody, A930008G09Rik antibody, crumbs 1, cell polarity complex component antibody, crumbs family member 1, photoreceptor morphogenesis associated antibody, CRB1 antibody, crb1 antibody, Crb1 antibody
    Background

    Synonyms: Protein crumbs homolog 1, CRB1

    Background: Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.

    Gene ID
    23418
    UniProt
    P82279
    Pathways
    Notch Signaling
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