CD47 antibody (Alexa Fluor 488)

Catalog No. ABIN6723946

This anti-CD47 antibody is a Mouse Monoclonal antibody detecting CD47 in FACS. Suitable for Human.

Quick Overview for CD47 antibody (Alexa Fluor 488) (ABIN6723946)

Target: CD47

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD47 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: MIAP410

Product Details anti-CD47 Antibody (Alexa Fluor 488)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD47

Target: CD47

Alternative Name: // CD47

Background:

Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP

Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Gene ID: 961, 16423, 29364

UniProt: Q08722, Q61735, P97829