MEK1 antibody (pSer218, pSer222)

Catalog No. ABIN6735714

The Mouse Monoclonal anti-MEK1 antibody (ABIN6735714) specifically detects MEK1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for MEK1 antibody (pSer218, pSer222) (ABIN6735714)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MEK1 Antibody

Binding Specificity: pSer218, pSer222

Specificity: Recognizes human, mouse and dog MKK1 phosphorylated at Ser218/222.

Cross-Reactivity: Dog (Canine), Mouse (Murine)

Purification: Thiophilic Adsorption Chromatography

Immunogen: Synthetic peptide corresponding to MKK1 (MAP kinase kinase 1) phosphorylated at Ser218/222.

Isotype: IgG1

Application Details

Application Notes: ELISA (0.1 µg/mL), WB (0.5 µg/mL)

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS, 0.09% sodium azide, PEG, sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: MAP2K1 / MEK1

Background: Standard Gene Symbol: MAP2K1, Gene Family: Protein Kinase, Gene Subfamily: MAP2K, Synonyms: MAP2K1, ERK activator kinase 1, MAPK/ERK kinase 1, MAPKK 1, MKK1, PRKMK1, MEK 1, MAP kinase kinase 1, MAPKK1, MEK1

Gene ID: 5604

UniProt: Q02750

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling